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The reports relating to effectiveness of carbenoxolone (nonselective 11-HSD inhibitor) in reducing central obesity are conflicting (219)
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However, for those with dietary restrictions or absorption issues, supplementation may be necessary

or when there is trauma, says Jandes
GLP-1-oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice
