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identified 1,2-dioxolane (FINO2) as the fourth class of chemicals able to induce ferroptosis ( Cells maintain a labile iron pool of Fe (II), linked to low-molecular-weight compounds, such as GSH
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However, current hepcidin or minihepcidins alternative strategies require parenteral administration

In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]

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