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glutathione content in borrelia Lyme Disease Pathogenesis BBE31 from the Lyme disease
Description
doi: 10.1371/journal.pmed.1004930

Merghany R

This could explain the observed increase in protein carbonylation despite unchanged TBARs levels (75)

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Ribonucleosides (adenosine, guanosine, inosine) are first degraded to their respective bases (adenine, guanine, hypoxanthine) by purine nucleoside phosphorylase (PNP), then salvaged to NMPs via PRPP-dependent enzymes adenine phosphoribosyltransferase (APRT) and hypoxanthineguanine phosphoribosyltransferase (HGPRT) [37, 38]

The mitochondrial electron transport chain (ETC) and NADPH oxidase (NOX) are key sources of ROS in -cells, and their dysfunction further promotes oxidative stress
