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What they found: In normal obese mice: AOD-9604 reduced body fat by 21 % vs placebo, hGH by 24 % The AOD-9604 effect was fully dependent on the 3-adrenergic receptor , in knock-out mice no effect The hGH effect was partly independent of 3-AR , in knock-out mice there was still ~10 % fat reduction AOD-9604 did not raise IGF-1 (control level), whereas hGH raised IGF-1 by 80 % No changes in growth, organ weights (except adipose tissue), fasting insulin Why it matters: The study provided the mechanistic basis for AOD-9604 and confirmed the key business hypothesis: it is possible to separate the lipolytic effect of GH from its growth effect

This therapeutic potential has been confirmed in lung (85) and breast cancers (86)

Its effective cellular permeability and membrane passage have already been demonstrated, which supports its use across a variety of tissue types

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A short conversation about how you feel, your goals, and your history helps us give you safe, comfortable care and helps you get the most out of each visit

Indications: For vitamin B12 deficiency that cannot be remedied through diet