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IFFO1 / cells exhibited a significant increase in PI3K and phosphorylated Akt expression, indicating the activation of the PI3K-Akt signaling pathway (Fig

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The APE1 inefficiently cleaves but recruits various transcription factors to activate downstream genes, such as vascular endothelial growth factor (VEGF) and endonuclease IIIlike protein 1 (NTHL1) [95]

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