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De Ita JR, Castilla-Cortzar I, Aguirre GA et al (2015) Altered liver expression of genes involved in lipid and glucose metabolism in mice with partial IGF-1 deficiency: an experimental approach to metabolic syndrome

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This makes it vital to energy metabolism in all living organisms

Its legacy lives on through the hundreds of generic injectables and infusion systems that continue to be widely used in hospitals today.