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These genetic mutations contribute to the multifaceted nature of ALS, causing disruptions in protein homeostasis, RNA metabolism, DNA repair, excitotoxicity, endosomal/vesicular transport, and neuroinflammation (144)
2d) in the presence of SAM suggests potential crosstalk communication between regulatory domains from neighbouring CBS proteins (inter-dimer) in the filament (Supplementary Movie 1)
10.1038/nature05859 Nature 97 YamamotoM.KenslerT
Spinal muscular atrophy: the past, present, and future of diagnosis and treatment
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Food Allergy and Intolerance: A Narrative Review on Nutritional Concerns
