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Regulation of Postsynaptic Receptors In PFC neurons, MPH indirectly activates the postsynaptic DRD1 and DRD5 [142] that uptake DA and transmit the signal in postsynaptic neurons [175]

The evidence base is largely preclinical (animal and cell) research on the individual components, supplemented by practitioner-derived protocols

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Not only can a deficiency in vitamin B12 cause schizophrenia, but vitamins B6 and B9 can also contribute to the condition, and symptoms can be reduced by supplementing these vitamins alongside antipsychotics (70)