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Among them, various signaling pathways as drug targets have been investigated, such as TNF, PDGF, JAK-STAT, PGE2, PDGF, NADPH oxidase, integrin inhibition, mTOR inhibition, and so on

Salazar-Arredondo E, et al

Furthermore, its ability to support mitochondrial function could make it a valuable adjunct therapy for mitigating the toxicity of certain chemotherapeutic agents

Thus, mitochondria function as both the source and target of toxic ROS since mitochondrial dysfunction and OS are important in aging and neurodegenerative diseases, including AD (7)

doi: 10.1016/j.bcp.2009.03.021
