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Data were independently extracted by two reviewers into a standardized spreadsheet, and pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using a random-effects model

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The natural history of cystinosis includes multisystem complications, the most prominent being glomerular failure at 910 years

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TB-500 enhances MMP-2 expression to facilitate cellular migration through provisional matrix while stimulating synthesis of ECM components including collagen types I and III, fibronectin, and hyaluronic acid essential for tissue reconstruction