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Early human trials showed a promising signal that a larger pivotal trial did not replicate, and the compound today sits in an unusual regulatory position: GRAS-designated as a food ingredient, but not an approved drug

Furthermore, immune dysfunction leads to altered balance within the immune pathways resulting in excess inflammation

Some patients may experience mild swelling or bruising afterward

Use caution if you have diabetes, liver or kidney disease, cardiovascular disease, or a history of eating disorders

always assess B12 directly

The synthetic form, cyanocobalamin, is the form most commonly used in supplements and foods, as it is cheap to produce