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doi: 10.1161/HYPERTENSIONAHA.123.20481

doi: 10.1016/j.freeradbiomed.2013.05.014 165 NgMYWCharsouCLapaoASinghSTrachsel-MonchoLSchultzSWet al

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A deficiency can lead to megaloblastic anaemia, a condition that causes symptoms like weakness and fatigue

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Tracing the Met farther back to its origins one finds that the generation of its reduced S is, indeed, NADPH-dependent