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KPV can help modulate this initial inflammatory response, facilitating the transition to the repair phase
in contrast, an immune-cold TME with MDSCs, TAMs, and Tregs allows tumor growth and progression
The Lancet Frias JP, et al
Janicka A, Szymanska-Pasternak J, Bober J
Modern day therapeutics that are recombinant DNA based have minimized the issue of heterogeneity, however aggregates are still present to some extent in all drug formulations and need to be studied further
