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Apelin-13 can activate the expression of SFXN1 and nuclear receptor coactivator 4 (NCOA4), thus leading to ferroptosis via ferritinophagy and transport of cytoplasmic Fe 2+ into mitochondria [44]

In this regard, we speculate that the irrelevance of this study may stem from the method of Se measurement, which is available in whole blood, serum (79, 80), urine (81), nails (82), and questionnaires (83)

Liposomal forms are typically more expensive

In all, it appears that an ideal treatment would target thrombosis or platelet aggregation, without increasing the risk for bleeding

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As the copper is chelated by the polymer, the peak obtained by SEC at 295 nm, which corresponds to the functionalized polymer, continuously increases with the copper concentration until a saturation of all DOTAGA chelating species is achieved, as shown in Fig