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It is found that curcumin can downregulate Bcl-2 and upregulate Bax, promoting the activation of caspases and poly (ADP-ribose) polymerase (PARP), ultimately facilitating caspase-dependent cell death, including osteosarcoma (Dhule et al., 2014), breast cancer (Low et al., 2022), and HeLa cancer cells (Ahmadi et al., 2017)

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some of these have since been proposed as biomarkers of cancer risk and prognosis [78,79,80]

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The emergence of a host immune response to the microbiome also contributes to the pathogenesis of COPD

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Author Contributions A.S.: original writing

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Detox & Liver Function: Promotes detoxification and supports liver repair

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For instance, Nimptsch et al

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