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In addition to serving as a supplement, it has also been incorporated into many dogs diets

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Amide linkages are characterised by partial double-bond character due to resonance stabilisation between carbonyl and nitrogen atoms

Velho et al

Dena Dubals lab at UCSF (Cell Reports, 2017) showed that peripheral klotho fragment administration enhanced cognition and neural resilience in young, aging, and -synuclein transgenic mice through NMDA receptor-dependent mechanisms