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Hepatocellular carcinoma (HCC) Sorafenib is widely used in the treatment of advanced HCC, and inducing ferroptosis of HCC cells is an important mechanism for the biological effects of sorafenib

The antioxidant system In the face of oxidative damage caused by iron overload, intracellular antioxidant systems prevent cell death due to lipid peroxidation

HO-1 is involved in a variety of pathological mechanisms of diabetic complications, especially inflammation and cell death caused by oxidative stress

It also contains a rich blend of highly purified glutathione with niacinamide and sodium ascorbyl phosphate (vitamin C) to support clearer, more even-toned skin and a brighter complexion

4547 In addition, SR-BI deficient macrophages exhibit lipid engorged lysosomes which are enriched in FC, which is consistent with the role of SR-BI in autophagy