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286 Frataxin (FXN), whose deficiency (mostly due to genetic GAA repeat expansions in the FXN gene, impairing its transcription) is causative for Friedreichs ataxia (FRDA), and a putative iron chaperone that contributes to the assembly of ironsulfur proteins

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doi: 10.1111/bjh.12950

This is because stomach acid plays a role in separating B12 from the protein its bound to in food, allowing for proper absorption

Broader Lesson AOD-9604 serves as an instructive case in peptide pharmacology, a molecule that demonstrated intriguing biological activity but failed to achieve clinical utility

Code availability In-house codes were previously used in the published works