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It is also important to note that products sold as AOD 9604 are often presented as injectable preparations, though some are marketed in oral or topical forms with unknown absorption and unverified quality

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For example, if the current frequency is 3-monthly then change to 6-monthly

For active cirrhosis: 1200 mg, once daily, intravenous drip, for 30 days

doi: 10.1016/j.mehy.2020.110412 34 CastejonA

Polymorphisms in the CYP2D6 and CYP3A5 genes, for example, can alter the metabolism of metoprolol and amlodipine, respectively, and influence optimal dosing regimens [179,180]