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Additionally, acupuncture also inhibits the expression of ACSL4 in MCAO/R rats model, an enzyme critical for incorporating PUFAs into membrane phospholipids, thereby reducing susceptibility to ferroptosis

OS injury drives diabetes and vascular complications, accelerating endothelial dysfunction [175]

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A meta-analysis by Lan et al

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Acetyl-CoA carboxylase 1 (ACC1), the rate-limiting enzyme in FA biosynthesis, which is negatively regulated by TRIB3 46 , was markedly reduced in Cse / mice compared with in Cse +/ mice on the no-Cys diet (Figs