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We discuss how copper also plays a key role in proteostasis and interacts either directly or indirectly with many of the key aggregate-prone proteins implicated in ALS, such as TDP-43, C9ORF72, SOD1 and FUS as well as the effect of their aggregation on copper homeostasis

The methyl group is converted into formaldehyde
Science 363 , 12171222 (2019)

Some people with mild cases dont need treatment

A comprehensive 2016 review described BPC-157 as a "dopamine system stabilizer" it doesn't simply increase or decrease dopamine, but appears to normalize dopaminergic function in both directions (Sikiric et al., 2016)

95 Zhou, X
