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The opposite is EC50 - half maximal effective concentration

A study performed in mice supplemented nutritionally with 400 mg/kg/day of synthetic NR showed an increase in NAD + levels in muscle and liver tissue (Cant et al., 2012)

Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies

However, results can vary widely, and more extensive research is needed to fully understand its long-term effects and optimal usage

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