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HUVECs (P3-5) were plated in 6-well plates 24 h prior to transfection

PMID: 10223088 Our findings suggest that acetaminophen administration selectively depletes (within 2 hr) mitochondrial glutathione, and produces local toxicity by altering membrane permeability and decreasing the efficiency of oxidative phosphorylation

10.1007/s12026-013-8384-0 4 AnsariM

Shen H, Tsuchida S, Tamai K and Sato K

The controlled release of DNAzymes, the maximal cytocompatibility, and significantly improved BBB permeability suggest that our DNZ-NLPs offer a promising formulation for delivering all types of oligonucleotides to the brain for neurodegenerative disease treatments

Enhancing the cell permeability and metabolic stability of peptidyl drugs by reversible bicyclization