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These observations underscore an important therapeutic implication for MASLD, showing that the timing and disease stage may be critical for maximizing the protective effects of GSH depletion, with the greatest benefit likely occurring during early, lipogenesis-driven phases of MASLD progression

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Flavones, including luteolin have shown therapeutic potential and can contribute to the treatment of neurodegenerative diseases

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Dexamethasone induces ferroptosis Via P53/Slc7a11/Gpx4 pathway in glucocorticoid-induced osteonecrosis of the femoral head