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Loss of merlin in the nucleus leads to overexpression of membrane proteins, including growth factor receptors and integrins, and activation of growth factor receptors influences cellcell contact inhibition

Before examining specific examples of nail disorders, this chapter reviews the anatomy and physiology of the toenail and supporting structures, to facilitate an understanding of the pathologic conditions

Combining Versant 2.0 and available sequencing results, the definitive (sub)types assigned were as follows: 1b ( N = 46, 44.2%), 6 non-a/non-b ( N = 41, 39.4%), 1a ( N = 7, 6.7%), 6a or b ( N = 5, 4.8%), 2 ( N = 4, 3.8%) and 3 (1.0%)

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