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For example, the important MTHFR enzyme, which contains more than 500 amino acids and has a molecular weight exceeding 77,000, is susceptible to mutations [5]
doi: 10.1111/j.1432-1033.1980.tb04605.x

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Irritability, anxiety, insomnia, or headaches: This means you could have a problem with glutamate and Reactive Oxygen Species

Esteller M, Levine R, Baylin SB, Ellenson LH, Herman JG

The samples for hepatic metabolomics analysis were part of a larger metabolomics study of the plasma, kidney, heart, and lungdata from which have been reported 6,15
