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doi: 10.1016/j.lfs.2005.05.103 46

Iliff JJ, Wang M, Liao Y, et al

TMAO has a high turnover rate, with more than 90% excreted in the urine after being metabolized by the kidney (49)

Therefore, the objective of this study was to use a metabolomics approach to evaluate metabolic signatures and gene set and pathway enrichment in (1) dogs based on disease (DCM or healthy), diet (non-traditional [NT] or traditional [T]), and their interactions and (2) dogs with DCM not associated with diet (presumably, dogs with primary DCM) compared to dogs with secondary, diet-associated DCM

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