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SIRT3 as a potential therapeutic target for heart failure
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A stress response pathway that responds to various cellular insults, including amino acid deprivation, through the GCN2 kinase, to phosphorylate eukaryotic translation initiation factor 2 (eIF2), halt general cap-dependent protein translation and increase transcription of endoplasmic reticulum chaperone proteins

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N-acetylcysteine, or NAC, is a modified version of L-cysteine

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