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Impairment of complex I leads to increased ROS production and decreased ATP synthesis, contributing to neuronal energy deficits and cell death [161]

Understanding the extent to which -CC contributes to root system plasticity under salinity will be critical for determining its broader significance in plant stress adaptation and its potential as a tool for improving crop resilience

Likewise, astrocytic overexpression of Nrf2 in a mouse model of ALS both delayed onset and increased survival, as did treatment with chemical Nrf2 inducers [26, 27]