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Sorafenib triggers ferroptosis via inhibition of HBXIP/SCD axis in hepatocellular carcinoma

10.2147/DMSO.S346007 133 WangY.TakanoT.ZhouY.WangR.ToshimitsuT.SashiharaT.et al (2023)

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Beltramo G., Cottenet J., Mariet A.-S., Georges M., Piroth L., Tubert-Bitter P., Bonniaud P., Quantin C

Proc Natl Acad Sci U S A 99:1598315987

By inhibiting SNHG29, simvastatin reduces YAP stability, leading to negative transcriptional regulation of PD-L1 and potentiating the antitumor immune response (99)

Although uncomfortable, these symptoms should pass in about a week or less
