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Reitman adjusts the schedule based on follow-up blood work

Supplementation at doses such as 2000 IU/day has demonstrated associations with reduced repetitive behaviors, improved eye contact, and better social engagement

B12 deficiency can manifest in a wide range of symptoms, some of which may be subtle or mistaken for other health conditions

As for clinical correlates, Vit B12 deficiency and HHcy do predict more rapid motor progression and cognitive dysfunction among PwPD and thus modulate PD clinical phenotypic variability

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