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In addition, PD smokers are less likely to die from neurologic causes compared to PD nonsmokers, and smokers were observed to have a lower levodopa (L-dopa) equivalent dose, a proxy of disease severity (Yoon et al., 2023)

Li L, Tian E, Chen X, Chao J, Klein J, Qu Q, Sun G, Sun G, Huang Y, Warden CD, Ye P, Feng L, Li X, Cui Q, Sultan A, Douvaras P, Fossati V, Sanjana NE, Riggs AD, Shi Y 2018 GFAP mutations in astrocytes impair oligodendrocyte progenitor proliferation and myelination in an hiPSC model of Alexander disease

The circadian clock maintains cardiac function by regulating mitochondrial metabolism in mice

[DOI] [PubMed] [Google Scholar] 163.Hagen D.M., Ekena J.L., Geesaman B.M., Viviano K.R

Indeed these are all probably best classified under the umbrella of post viral fatigue syndrome
Selenium contributes to the protection of cells from oxidative stress and to the normal function of the immune system
