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Lim Y, Vasu VT, Valacchi G, Leonard S, Aung HH, Schock BC, et al

PMID: 38416404

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J., Mommsen P., et al., Systemic Inflammatory Effects of Traumatic Brain Injury, Femur Fracture, and Shock: An Experimental Murine Polytrauma Model, Mediators of Inflammation 2012 (2012): 136020, 10.1155/2012/136020

(89) in animal models confirmed that SIN attenuates inflammation by inhibiting both NF-B and MAPK signaling pathways, leading to the downregulation of pro-inflammatory cytokines, such as IL-6 and TNF-