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Therapy of autoimmune inflammation in sporadic amyotrophic lateral sclerosis: dimethyl fumarate and H-151 downregulate inflammatory cytokines in the cGAS-STING pathway

However, this route may result in lower tissue concentrations at specific target sites compared to localized injection or topical application (Pickart et al., 2015)

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Another metabolic product of intestinal bacteria, urolithins (UA), is produced through the conversion of dietary ellagitannins and ellagic acid by specific gut microbiota

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