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Antioxidants can become pro-oxidants

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337 While effective in enzyme level detection, the conventional dithiol flanking design of nanoparticle assembly suffers from the absence of hydrophilic domains necessary to maintain a balance between water solubility and responsiveness

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Likewise, the tumor model, and critically, the TME, must reflect the cancer under study, particularly ones that are less immunogenic or hard to treat

References Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE
