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The result is selective apoptosis of FOXO4-high senescent cells, leaving FOXO4-low non-senescent cells intact a selectivity that makes it a uniquely powerful molecular probe for studying the contribution of senescent cell accumulation to tissue dysfunction, ageing phenotypes, and disease biology

Peer review Peer review information Nature Reviews Drug Discovery thanks Michael Nauck, Stefan Trapp and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

10.1038/s41577-019-0125-8 Nat

Anti-Doping Agency (USADA) Sport Integrity Australia and related communications state it is not approved by the TGA

But sleep cycles aren't as clear-cut as people think

The tripeptide-copper complex has been the subject of published research for over five decades, with mechanistic literature accumulating around its role in gene expression regulation, extracellular matrix biology, and copper-mediated cellular signaling