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In contrast, overexpression of G6PD limits endothelial oxidant stress and increases nitric oxide levels (55)
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Proteasome dysfunction activates autophagy and the Keap1Nrf2 pathway
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Future studies should correlate molecular markers with clinical outcomes
47,48 This is partly due to limitations in the ability to quantify the risk of cancer in patients with a rare disease and differences in the methodological approaches
