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Activation of PGC-1 also prevents renal dysfunction in various renal diseases and has emerged as a potential therapeutic target against renal aging (70, 71)

Lee, J.D., Nunes, E.V., Novo, P., et al

Understanding their relationship helps clarify dosing comparisons

I tried to get methyl as Id already had that for loading doses
FOXO4 knockdown resulted in increased levels of p53 and Ser15-phospho-p53, but paradoxically decreased the level of p21

b Graded per NCI CTCAE version 4.03
