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[PubMed: 20183830] 132
In a double blind, placebo-controlled, phase III study, benfotiamine was effective in lowering the neuropathy symptom score, even though total symptom score was not changed after treatment

Histamine Intolerance Causes Understanding histamine intolerance causes is essential before choosing treatment

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79 Thus, it will be interesting to examine the dynamic regulation of ion transport during inflammatory events, and whether there is a causal contribution of claudin-2 in such regulation

Concise Answer: No, it has risks, although serious complications are rare when proper protocols are followed
