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Intrathecal metformin injection significantly reduced methylglyoxal levels and RAGE upregulation in the dorsal horn of the spinal cord in a rat model of BIPN, effectively blocking BTZ-induced central sensitization and mechanical pain abnormalities (Wei et al., 2017)
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Both the greater and lesser tubercles serve as attachment sites for muscles that act across the shoulder joint
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Zhang SJ, Li YF, Wang GE, Tan RR, Tsoi B, Mao GW et al (2015) Caffeine ameliorates high energy diet-induced hepatic steatosis: sirtuin 3 acts as a bridge in the lipid metabolism pathway
