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What Clinical Research Shows Theory matters, but clinical evidence matters more

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In the case of the JNK inhibitor SP600125, which is only soluble in DMSO and requires early treatment, 70% of the protection against APAP toxicity was caused by DMSO and 30% by SP600125 [36]

Plant J 54:10631075 Gromes R, Hothorn M, Lenherr ED, Rybin V, Scheffzek K, Rausch T (2008b) The redox switch of gamma- glutamylcysteine ligase via a reversible monomer-dimer transition is a mechanism unique to plants

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An analysis of the chemical shifts clearly indicates that the pressure dependence of some resonance lines cannot be described by the quasi-sigmoidal dependence characteristic for a two states model