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Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS

Context-dependent indicates heterogeneity across tissues, disease stages, or models

[Google Scholar] 23.Pettegrew JW, Levine J, Gershon S, et al

The stomach produces it, which may be part of why it has such a broad cytoprotective profile: the gastric mucosa lives in a uniquely hostile environment and regenerates continuously

10.1182/blood-2015-05-642223 168

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