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Simcox J, Geoghegan G, Maschek JA, Bensard CL, Pasquali M, Miao R, et al

Elevated TMAO levels have been linked to a number of diseases, including cardiovascular and neurological disorders, renal disease, metabolic syndrome, obesity, type 2 diabetes (T2D), non-alcoholic fatty liver disease (NAFLD), cancer, and severe COVID-19

Somfai T, Kaneda M, Akagi S, Watanabe S, Haraguchi S, Mizutani E, Dang-Nguyen TQ, Geshi M, Kikuchi K, Nagai T

Carnitine has previously attracted the attention of scientists because it has two very important functions that help regulate energy use: It assists the movement of fats across membranes within your muscle mitochondria (the energy factories that power muscle cells) for both aerobic energy production, and recovery between anaerobic efforts

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Cells were grown to 85%95% confluence before they were placed in a humidified 37 C incubator, and cells from passages 520 were used