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Patients receiving the higher dose range had much higher survival rates than patients receiving the lower dose range: The higher dose range had an 86% 1-year survival rate The lower dose range had a 59% 1-year survival rate Additionally, there was not any evidence of increased toxicity or safety concerns from the higher doses

4e, f and Supplementary Figs

[DOI] [PMC free article] [PubMed] [Google Scholar] Liu Y

Although the primary outcome of the study was the safety of mannitol, clinical and biochemical measures were collected as secondary outcomes, but none of those outcomes were different between the group receiving mannitol and controls

LiangYLiuZQuLWangYZhouYLiangLet al

doi: 10.1378/chest.14-2434 6 NgT-PNitiMTanW-CCaoZOngK-CEngP