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& Hamouche, L
The PYCR1 gene is located on chromosome 17q25.3 and is composed of 9 exons that generate six alternatively spliced mRNAs that collectively encode five different isoforms of the enzyme
It could be expressed also as the urinary drug excretion rate (dDu/dt) divided by the plasma drug concentration: For any drug cleared by the kidney, the rate of drug passing through the kidney must equal the rate of drug excreted in the urine
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J Mol Neurosci 66(2):197206
During your initial consultation, Dr
