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When assessed using Relational database of Metabolomic Pathways (RaMP-DB) that has 3694 metabolite and lipid pathways integrated from KEGG, HMDB, Reactome and WikiPathways, the significant pathways were Oligodendrocyte specification and differentiation leading to myelin components for CNS, Immunoregulatory interactions between lymphoid and non-lymphoid cells, Kennedy pathway from sphingolipids, MTHFR deficiency, Sphingolipid pathway and Glycerolipids and glycerophospholipids

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Injection site selection The preferred injection site depends on the treatment goal

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Irrespective of the current body of research and significant improvement, a lot remains to be learned about the topical use of nanotechnology as a treatment measure towards skin disorders