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[DOI] [PubMed] [Google Scholar] 457.Rtig, A

Vimentin-positive astrocytes in the prefrontal white matter show fewer primary processes 400

6.3 Ferroptosis of astrocytes promotes atherosclerosis Astrocytesthe most abundant and largest class of glial cells in the mammalian brainmaintain and divide neuronal cells, aid in creating the blood-brain barrier, and regulate the onset of several disease processes (Khakh and Sofroniew, 2015)

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So, if you're low in B12, then fatigue and general weakness are going to be one of the main symptoms