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We confirm that C-PC selectively targets GBM cells by enhancing cellular uptake in resistant phenotypes while sparing normal cells, and that C-PC-CDDP combination therapy enhances cytotoxicity significantly in treatment-sensitive U87 cells through apoptosis induction and ROS modulation, the latter involving upregulated MnSOD and catalase expression, and C-PC monotherapy offers superior efficacy compared to combination treatment in CDDP-resistant U87-EGFRvIII cells

niacin or niacinamide ( n = 4)

Sci Rep 11 , 3034 (2021)

Like most herbals, long-term use (e.g., more than 23 months) should be minimized

A study involving the cortex of juvenile and adult Fmr1- KO mice has revealed impaired mitochondrial energy metabolism

In her now deleted Instagram photo, Mariel was seen with an intravenous (IV) drip in the Senate office with her husband, Senator Robin Padilla behind her