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Despite a castrate level of testosterone, CRPC almost uniformly remains dependent on AR signalling

Acetyl L-Carnitine does and that distinction matters significantly for cognitive support.* Once in the brain, ALC supports the production and activity of acetylcholine, a neurotransmitter involved in memory, focus, and overall cognitive function.* It also supports mitochondrial function in brain cells, contributing to the same energy production pathway that CoQ10 supports throughout the rest of the body.* In peripheral tissues, Acetyl L-Carnitine performs a critical transport function shuttling long-chain fatty acids across the mitochondrial membrane so they can be used as fuel

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It is essential for the transport of long-chain fatty acids into the mitochondria where they can be metabolized to produce energy
