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Free Radicals and ObesityRelated Chronic Inflammation Contrasted by Antioxidants: A New Perspective in Coronary Artery Disease. Metabolites 13, no

10.15761/IMM.1000389 Lubos E, Loscalzo J, Handy DE (2011) Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities

This process thereby downregulates the NF-B pathway, augments Treg differentiation, and suppresses Th17 expansion and inflammatory cytokine release (215, 216)

(b) reduction of inflammation by modulating the inflammasome and increasing lipoxin A4 expression

Categorization of metabolites We used the Human Metabolome Database (HMDB) (www.hmdb.ca) to classify the metabolites into seven categories: energy, carbohydrate, nucleotide, amino acid, peptide, lipid, and others